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Trijani Suwandi, drg, Sp. Perio

• Dentist, graduated from Faculty of Dentistry, Trisakti University, year 1993
• Graduated in Periodontics, Faculty of Dentistry, University of Indonesia, year 2003
• Lecturer in Periodontology Department, Faculty of Dentistry, Trisakti University, Jakarta, Indonesia
• Practice :
     - Clinical Specialist in Periodontology, Dental Hospital Trisakti University, Jakarta, Indonesia.        Telp (+62 21) 5672731 ext. 1709
     - Citra Garden 1 ext. AD-2 no. 15 West Jakarta. Telp (+62 21) 5403753
CLINICAL EFFECTS OF THE SUB GINGIVAL APPLICATION BETWEEN 25% METRONIDAZOLE GEL
AND 10% POVIDINE-IODINE AS ADJUNCTIVE THERAPY OF SCALING
AND ROOT PLANING IN CHRONIC PERIODONTITIS
Trijani Suwandi
Participant of Educational Program for Periodontic Specialist
Trijani Suwandi : Clinical effects of the subgingival application between 25% metronidazole gel and 10% povidine-iodine as adjunctive therapy of Scaling Root Planing (SRP) in Chronic Periodontitis. Journal of Dentistry University of Indonesia, 2003:10 (Special Edition), 669-674.
Tabel I. Mean and Standard Deviation of the Dental Pocket Depth Before and After the Application of 25% Metronidazole gel, 10% PVP-1 Solution and Control of 90 Teeth After Scaling and Root Planing
n Before treatment
mean +sd
After treatment
mean +sd
Differences
mean +sd
p
25% Metronidazole 30 6,400 + 0,563 2,033 + 0,809 4,367 + 0,718 0.000
10% PVP-1 30 6,267 + 0,521 3,900 + 0,662 2,367 + 0,615
Control 30 6,300 + 0,466 4,533 + 0,776 1,767 + 0,626
One way Annova, n = number of samples, sd = standard deviation, p = probability

Tabel II. Mean and Standard Deviation of the Attachment Loss Before and After the Application of 25% metronidazole gel, Povidon-Iodon 10% Solution and Control of 90 Teeth After Scaling and Root Planing
n Before treatment
mean +sd
After treatment
mean +sd
Differences
mean +sd
p
25% Metronidazole 30 7,933 + 1,172 3,367 + 1,326 4,567 + 0,679 0.000
10% PVP-1 30 7,767 + 1,165 5,067 + 1,285 2,700 + 0,794
Control 30 7,267 + 1,048 5,933 + 1,363 1,333 + 0,661
One way Annova, n = number of samples, sd = standard deviation, p = probability

Different results, either before or after treatments, were analyzed using Kruskal-Wallis test and they showed significant differences in which p < 0.01. In multiple analysis, there was less gingival bleeding with the ranks as follows : 25% metronidazole gel (R difference = 3459, 10% PVP-I solution (R difference = 2308), and control (R difference = 1923). The differences in reducing pocket depth can be measured using Annova test, like in table 1, which are very significant (p = 0.000). At average, the reducing pocket depth are ranked as follows : 25% metronidazole gel, 10% PVP-1 solution and control. The differences is reducing the attachment loss are measured by Annova test as per table 2 which are very significant (p = 0.000). Furthermore, the average of attachment mounting is ranked as follows : 25% metronidazole gel, 10% PVP-1 solution, and control.
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